Patient Exhalation Simulator PES For the evaluation of inhaler misuse conditions and device robustness Exhalation into the mouthpiece of an inhaler prior to the inhalation step is a commonly reported error in patient technique, particularly for dry powder...
More
Patient Exhalation Simulator PES For the evaluation of inhaler misuse conditions and device robustness Exhalation into the mouthpiece of an inhaler prior to the inhalation step is a commonly reported error in patient technique, particularly for dry powder inhaler (DPIs). The consequence of this poor technique may be insufficient drug delivery for effective administration and ultimately, inadequately controlled respiratory disease and/or an over- reliance on emergency medication. The Patient Exhalation Simulator (PES) accurately replicates the effects of a patient exhaling into the device mouthpiece prior to the inhalation step. The warm, humid air generated by the PES can be set at flow rates representative of different human exhalation profiles. The PES enables developers to assess how device misuse impacts the critical quality attributes of the inhaler, empowering device design optimisation to ensure robust drug delivery. Simple to set-up and easy-to-use Adjustable air flow temperatu
Less
