Resource A tridimensional atlas of the developing human head Graphical abstract Authors Raphael Blain, Ge´rard Couly, Eimad Shotar, ..., Paolo Giacobini, Yorick Gitton, Alain Che´dotal Correspondence yorick.gitton@inserm.fr (Y.G.), alain.chedotal@inserm.fr...
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Resource A tridimensional atlas of the developing human head Graphical abstract Authors Raphael Blain, Ge´rard Couly, Eimad Shotar, ..., Paolo Giacobini, Yorick Gitton, Alain Che´dotal Correspondence yorick.gitton@inserm.fr (Y.G.), alain.chedotal@inserm.fr (A.C.) In brief Using advanced whole-mount immunostaining and 3D imaging, a comprehensive 3D cellular atlas of human head embryogenesis encompassing muscles, vasculature, cartilage, peripheral nerves, and exocrine glands is presented. The datasets are used to provide insights into the branching morphogenesis of exocrine glands and features of neurovascular and skeletomuscular structure development. Highlights d 3D imaging reveals the developmental sequence of human head organs during gestation d Salivary gland morphogenesis is asymmetric and shows interindividual variability d Virtual reality and interactive 3D tools improve our understanding of human development d Hudeca.com, a web interface and image database to explore and learn h
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