The Chromosomal Basis CHAPTER 12 of Inheritance Key Concepts 12.1 Morgan showed that Mendelian inheritance has its physical basis in the behavior of chromosomes: Scientific Inquiry 12.2 Sex-linked genes exhibit unique patterns of inheritance 12.3 Linked...
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The Chromosomal Basis CHAPTER 12 of Inheritance Key Concepts 12.1 Morgan showed that Mendelian inheritance has its physical basis in the behavior of chromosomes: Scientific Inquiry 12.2 Sex-linked genes exhibit unique patterns of inheritance 12.3 Linked genes tend to be inherited together because they are located near each other on the same chromosome 12.4 Alterations of chromosome number or structure cause some genetic disorders Figure 12.1 Where in the cell are Mendel’s hereditary factors located? Overview Locating Genes Along to develop the chromosome theory of inheritance. Chromosomes According to this theory, Mendelian genes have specific loci (positions) along chromosomes, and it is the chromosomes Today, we know that genes—Mendel’s “factors”—are segments that undergo segregation and independent assortment. of DNA located along chromosomes. We can see the location As you can see in Figure 12.2, the separation of homo- of a particular gene by tagging chromosomes with a fluorescent
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