Prolonged Neuropsychiatric Symptoms In A Military Service Member Exposed To Mefloquine~2016

Drug Saf - Case Rep (2016)3:7 DOI 10.1007/s40800-016-0030-z CASE REPORT Prolonged Neuropsychiatric Symptoms in a Military Service Member Exposed to Mefloquine Jeffrey Livezey1 • Thomas Oliver2 • Louis Cantilena2 ! The Author(s) 2016. This article is... More

Drug Saf - Case Rep (2016)3:7 DOI 10.1007/s40800-016-0030-z CASE REPORT Prolonged Neuropsychiatric Symptoms in a Military Service Member Exposed to Mefloquine Jeffrey Livezey1 • Thomas Oliver2 • Louis Cantilena2 ! The Author(s) 2016. This article is published with open access at Springerlink.com Abstract A 32-year-old male developed neuropsychiatric symptoms 2 weeks after starting mefloquine 250 mg/week Key Points for malaria prophylaxis. He continued to take the medi- cation for the next 4 months. Initial symptoms included Melfoquine-induced neuropsychiatric symptoms can vivid dreams and anxiety, as well as balance problems. be severely life debilitating. These symptoms persisted and progressed over the next 4 years to include vertigo, emotional lability, and poor Given the overlapping symptoms of post-traumatic short-term memory, which have greatly affected his per- stress disorder and mefloquine toxicity, it can be sonal and professional life. An extensive evaluation challenging to Less