ADC Case Study-Custom Synthesis of ADC Linker-payload SET

Presented here is a case study for the synthesis of two customized payload-linker complexes via the "DrugLnk" organic synthesis service. SN38 is the payload of choice and two cleavable ADC linkers are used to formulate the SN38-linker complexes. For the... More

Presented here is a case study for the synthesis of two customized payload-linker complexes via the "DrugLnk" organic synthesis service. SN38 is the payload of choice and two cleavable ADC linkers are used to formulate the SN38-linker complexes. For the protection of custom IP, the reaction conditions, catalysts, as well as solvents are omitted from the synthesis routes. Less