RESEARCH Open Access
Diagnostic value and prognostic evaluation of
Presepsin for sepsis in an emergency department
Bo Liu, Yun-Xia Chen, Qin Yin, Yun-Zhou Zhao and Chun-Sheng Li*
Abstract
Introduction: Presepsin levels are known to be increased in sepsis....
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RESEARCH Open Access
Diagnostic value and prognostic evaluation of
Presepsin for sepsis in an emergency department
Bo Liu, Yun-Xia Chen, Qin Yin, Yun-Zhou Zhao and Chun-Sheng Li*
Abstract
Introduction: Presepsin levels are known to be increased in sepsis. The aim of this study was to evaluate the early
diagnostic and prognostic value of Presepsin compared with procalcitonin (PCT), Mortality in Emergency
Department Sepsis (MEDS) score and Acute Physiology and Chronic Health Evaluation II (APACHE II) score in septic
patients in an emergency department (ED) and to investigate Presepsin as a new biomarker of sepsis.
Methods: This study enrolled 859 consecutive patients with at least two diagnostic criteria for systemic
inflammatory response syndrome (SIRS) who were admitted to Beijing Chao-yang Hospital ED from December 2011
to October 2012, and 100 age-matched healthy controls. Patients were stratified into four groups: SIRS, sepsis, severe
sepsis, and septic shock. Plasma Presepsin and s
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