131
ABSTRACT
A 45 year old female was diagnosed to have invasive ductal
carcinoma of left breast. Following mastectomy and adjuvant
chemotherapy and radiation therapy she progressed with brain
metastases. After palliative chemotherapy based on lapatinib
and...
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131
ABSTRACT
A 45 year old female was diagnosed to have invasive ductal
carcinoma of left breast. Following mastectomy and adjuvant
chemotherapy and radiation therapy she progressed with brain
metastases. After palliative chemotherapy based on lapatinib
and capecitabine the brain metastases resolved completely. We
report a patient with brain metastases from HER2 positive
breast cancer that was successfully treated with radiation and
a combination of lapatinib and capecitabine.
Complete Response of Brain Metastases in
HER2 Positive Breast Cancer after Treatment with
Lapatinib and Capecitabine
Mohd Shafi Moona, Arwa Nabhan, Farah Waqar.
Department of Medical Oncology, King Abdullah Medical City & Oncology Center, Jeddah, Kingdom of Saudi Arabia.
Key Words: Breast cancer, brain metastases, HER2 positive,
lapatinib.
INTRODUCTION
Patients with HER-positive breast cancer who have
been treated with trastuzumab are at greater risk for
developing brain metastasis with the incidence ranging
from
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